Therapy Products

PRODUCT / Therapy Products

KeraHeal

A Spray-Type Autologous Keratinocyte Therapy
Product for Wounds

Product Name KeraHeal
Indications Deep 2nd degree burns that cover more than 30%
of the total body surface area
3rd degree burns that cover more than 10%
of the total body surface area
Dosage 1 mL cell suspension / 100~400 cm2
Storage Refrigerated at 2~8℃

※ Visit http://ezdrug.mfds.go.kr/ for more information

Therapeutic Effects of KeraHeal

Engraftment
Rate (%)
KeraHeal Number of Patients
99.7% 10
100.0% 29
68.0% 16
Survival
Rate (%)
74.3%
(59.3% Without KeraHeal)
35

References

  • Journal of Korean Burn Society. 2007;10(2):112-7. Clinical Study of Autologous Cultured Keratinocyte Cell Spray "KerahealTM" on Severe Burn Wound.
  • Burns. 2011 Sep;37(6):1067-71. Clinical study of cultured epithelial autografts in liquid suspension in severe burn patients.
  • Burns. 2012 Sep;38(6):931-6. Outcomes of sprayed cultured epithelial autografts for full-thickness wounds: a single-centre experience.
  • Wound Repair Regen. 2015 May-Jun;23(3):340-4. The application of cultured epithelial autografts improves survival in burns.

  • Human Epidermal Keratinocytes

  • Expression of p63
    (A Marker for Skin Stem Cells)

KeraHeal-Allo

A Thermosensitive Hydrogel-Type Allogeneic
Keratinocyte Therapy Product

Product Name KeraHeal-Allo
Indications Promotes the re-epithelialization of deep 2nd degree burns
Dosage 1.5 mL cell suspension(2×107 cells) / 100 cm2
Storage Frozen at -15 ~ -25℃
Shelf Life 18 months from production

※ Visit http://ezdrug.mfds.go.kr/ for more information

Therapeutic Effects of KeraHeal-Allo
(When Compared to Silicon Dressing)

Duration of
Re-epithelialization
(days)
KeraHeal-Allo
(N=30)
Mepitel
(N=30)
KeraHeal-Allo
(N=15)
Mepitel
(N=15)
11.5 ± 4.3 14.1 ± 4.3 9.6 ± 4.0 12.4 ± 4.8
〈0.0001 〈0.0001

References

  • Clinical Trial Reports for KeraHeal-Allo
  • Burns. 2014 Dec; 40(8): 1642-9. A clinical trial designed to evaluate the safety and effectiveness of a thermosensitive hydrogel-type cultured epidermal allograft for deep second-degree burns.