Human Tissue Models

PRODUCT / Human Tissue Models

Human Tissue Models

Produced from three-dimensional (3D) culturing cells-derived human tissue using tissue engineering technology, human tissue models are in vitro 3D organs structurally and functionally similar to the actual human tissue.
Human tissue models can be utilized for evaluation of toxicity and efficacy of therapeutics.

The skin model and corneal model made by Biosolution Co., Ltd. are undergoing national validation studies for registration as an OECD Test Guideline.

Human tissue models reconstruct micro-organs at the micrometer level on the basis of the 3D-culture technologies and are highly similar to the human tissue in terms of its histological, morphological and biochemical characteristics.

  • Epidermis Model
  • Pigmented Epidermis Model
  • Full Thickness Skin Model
  • Corneal Model
  • Oral Mucosa Model
  • Airway Epithelial Model
  • Liver Model
  • Islet Model
  • Neuronal Model

Biosolution’s skin model consists of four major layers called the stratum corneum, granular layer, stratum spinosum and basal layer, which are all expressed in the human skin. The skin model can be utilized for the evaluation of toxicity (skin irritation, skin sensitization, genotoxicity, phototoxicity etc.) and efficacy (skin permeation, skin barrier function, moisturizing, anti-aging, whitening etc.) of skin therapeutics and cosmeceutics.

The cornea model is used to develop ophthalmic therapeutics as an alternative to animal testing; it can be utilized for evaluation of toxicity and efficacy of ophthalmic therapeutics. Experimental results using our cornea model have been published in internationally accredited academic journals.